MersV1, Main, Exploration, bibRecord, 002572

Crystal structure of XMRV protease differs from the structures of other retropepsins

Identifieur interne : 002572 ( Main/Exploration ); précédent : 002571; suivant : 002573

Crystal structure of XMRV protease differs from the structures of other retropepsins

Auteurs : Mi Li [États-Unis] ; Frank Dimaio [États-Unis] ; Dongwen Zhou [États-Unis] ; Alla Gustchina [États-Unis] ; Jacek Lubkowski [États-Unis] ; Zbigniew Dauter [États-Unis] ; David Baker [États-Unis] ; Alexander Wlodawer [États-Unis]

Source :

Nature Structural & Molecular Biology [ 1545-9993 ] ; 2011-02.

RBID : ISTEX:81B60EC51965B864C1593E7AC49227EA89085376

Abstract

XMRV is a retrovirus that has been linked to prostate cancer and chronic fatigue syndrome. The crystal structure of the XMRV protease differs from the structures of other retropepsins and instead resembles those of pepsin-like enzymes, suggesting that this protease may represent a distinct evolutionary branch of the aspartic proteases.

Url:

https://api.istex.fr/ark:/67375/GT4-QFM116M3-2/fulltext.pdf

DOI: 10.1038/nsmb.1964

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="eng">XMRV is a retrovirus that has been linked to prostate cancer and chronic fatigue syndrome. The crystal structure of the XMRV protease differs from the structures of other retropepsins and instead resembles those of pepsin-like enzymes, suggesting that this protease may represent a distinct evolutionary branch of the aspartic proteases.</div>
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Crystal structure of XMRV protease differs from the structures of other retropepsins

Crystal structure of XMRV protease differs from the structures of other retropepsins

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri